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Statements Author contributions L-YH, conceived and designed the study and wrote the manuscript, YL and JB, collected data, S-QN and S-JL, revised the manuscript
Gaps: dosing, delivery, safety, and large RCTs remain
Isolaz is often called an acne laser, though its technically a light-based therapy
still, surveillance matters
While our knowledge of the structural and morphological changes in depression and how they impact pathogenesis and treatment are still evolving, it is important to realise that the use of supplements such as SILY that have validated adaptogenic, antioxidant, antiinflammatory, cognitive enhancing, anxiolytic, and neuroprotective effects could be valuable in depression management, although clinical studies and trials would be necessary to verify its usability in humans
